Immunohistochemistry was positive for S-100, alpha-antichymotrypsin, and the antigens CD1a and CD68.[23] The signs and symptoms of orbital RDD include exophthalmos (most frequent), lagophthalmos, blurred vision, diplopia, conjunctival congestion, dry eye, uveitis, and ocular irritation.[1]. The gene discussed is CD1A; the disease is Proptosis.