In this case, the patient met the diagnostic criteria of ABPA, including serum IgE >100 U/L, elevated A. fumigatus-specific IgG, HRCT infiltrates, central bronchiectasis, and A. fumigatus cultured from the sputum.[4] ABPA is a pulmonary disorder caused by hypersensitivity to A. fumigatus. The gene discussed is IGHE; the disease is allergic bronchopulmonary aspergillosis.