To detect the protein level of SGK196 during tumorigenesis, the tissue microarray chip including 63 cases of BC tissues and 8 cases of normal adjacent breast tissues was examined by immunohistochemistry and the data showed that SGK196 protein expression (brown staining area) is significantly increased in BC tissues comparing to the normal adjacent breast tissues (P < 0.0001) (Fig. 1b, c; Fig. S1B). This evidence concerns the gene POMK and breast cancer.