To examine whether the increased granulocytic subset due to loss of lamin A/C is responsible for enhanced lung metastasis, CD11b+Ly6G+ cells were depleted with Ly6G neutralizing antibody (Figure S2H), which showed a decreased number of metastatic nodules in E0771‐M1 tumor‐bearing LmnaMyeKO mice (Figure 2G). Here, ITGAM is linked to neoplasm.