Further, the differential uptake of TFP-MNPs in prostate and skin cancer cells is in agreement with our previous studies on the uptake of BPLP-MNPs and WBPLP-MNPs in PC3 and LNCaP cell lines where the more hydrophilic WBPLP-MNPs showed significant preferential uptake into PC3 cell lines relative to LNCaP cell lines 7. The gene discussed is OPRPN; the disease is skin cancer.