APC and neoplasm: The oncogenes affected at each U1 level, 204 in total, are listed in Supplementary Table 4 and include cell cycle regulation (CDC25A, CCNB1), apoptosis (BCL6, BRCA1), cell migration (FGFR1, FYN), extracellular matrix remodeling (TIMP2), signaling (EGFR), transcription (WNT5A), metastasis and tumor progression (EWSR1, APC, BRAF).