The oncogenes affected at each U1 level, 204 in total, are listed in Supplementary Table 4 and include cell cycle regulation (CDC25A, CCNB1), apoptosis (BCL6, BRCA1), cell migration (FGFR1, FYN), extracellular matrix remodeling (TIMP2), signaling (EGFR), transcription (WNT5A), metastasis and tumor progression (EWSR1, APC, BRAF). The gene discussed is CDC25A; the disease is neoplasm.