Human exome sequencing and genome‐wide association studies have revealed that mutations in SWI/SNF‐complex subunits are also linked to several neurodevelopmental disorders.16 Targeting SWI/SNF complexes offers moreover great potential for heart diseases17 as they play a critical role in cardiac development, congenital heart disease, cardiac hypertrophy, and vascular endothelial cell survival. The gene discussed is SMARCA1; the disease is neurodevelopmental disorder.