The expression profiles of profibrotic genes such as CYGB, ACTA2, PCDH7, DES, COL1A1, and COL1A3 were also significantly up‐regulated in the co‐culture NASH model, when compared with the steatosis model (Fig. 1G). The gene discussed is PCDH7; the disease is metabolic dysfunction-associated steatohepatitis.