HLA-C and tuberculosis: It is now possible to precisely identify peptide sequences, bound to MHC molecules, at the femto molar scale.7,8 This technology allowed the identification of epitopes presented by conventional HLA class-I molecules in ovarian cancer,9 influenza,10 hepatitis C,11 HIV,12 and TB.13 Unconventional class-I, HLA-E bound peptides have been identified in cells infected with M.tb.