Treatment for type 2 diabetes is targeted at the hyperglycemia arising due to a resistance to insulin action and an inadequate insulin secretory response.4 5 Lifestyle changes or pharmacotherapy aim to control blood glucose levels and avoid hyperglycemia and associated long-term complications,6–12 and these may also be supplemented with bariatric surgical intervention.13 The gene discussed is INS; the disease is type 2 diabetes mellitus.