Moreover, ISX‐GFP showed high binding activity to the above promoter elements of both Snail1 and TWIST1 with ISX cis‐binding element (IBE; the sequence “CGCCGC” is a potential ISX‐binding cis‐element; 17, 19) in lung cancer cells (Figs 1E and EV1A). Here, SNAI1 is linked to lung cancer.