TREM2 and Nasu-Hakola disease: Using our previously described techniques10 we generated human iPS‐Mg harboring polymorphisms implicated in Alzheimer’s disease (AD; R47H) and in Nasu Hakola disease (NHD; T66M/W50C) via mesodermal germ layer induction and primitive hematopoiesis (Supplementary Figure 2A‐C), with comparable microglial genetic profiles in multiple lines (Supplementary Figure 2D) harboring polymorphisms that give rise to differential TREM2 protein glycosylation and cleavage (Supplementary Figure 2E).