In our previous study, we focused on T-box transcription factor 21 (T-bet), which is the master regulator of effector T-cell activation, and showed significant relationships among NG3, high Ki67, PD-L1 positivity on tumor cells and CD8 positivity on immune cells in TNBCs with high T-bet-expressing TILs [21]. This evidence concerns the gene EGFL8 and neoplasm.