The anti-PEG antibodies have been further engineered for cancer-targeting therapy to universally deliver PEGylated nanoparticles to tumors by using bispecific PEG-binding antibodies that simultaneously bind to PEG on the nanomedicines and to membrane receptors (e.g., epidermal growth factor receptor, or EGFR) on the cancer cells [8–10]. The gene discussed is EGFR; the disease is cancer.