ORM2 and rheumatoid arthritis: Some of them were already described as glycoproteins [26, 47] such as thyroxine-binding globulin or beta-2-glycoprotein [1, 48, 49] some others as being involved in RA pathology [29, 30, 50] (e.g. alpha-1-acid glycoprotein 2 whose fucosylation and sialylation have shown to significantly increase in RA) [51] or other chronic inflammatory diseases [52–54].