To further confirm whether the effects of SNHG1 on PD pathogenesis were mediated by miR-153-3p, SH-SY5Y cells were transfected with miR-NC, miR-153-3p, miR-153-3p + pcDNA, or miR-153-3p + pcDNA-SNHG1 prior to MPP+ treatment. The gene discussed is SNHG1; the disease is Parkinson disease.