NEK5 and neoplasm: NEK5 quantitative analysis on the other hand showed high expression in patients with invasion (p = 0.0424) and metastasis (p = 0.0108); also NEK5 was more expressed in patients with larger tumours (tumour size > 4 cm; 195.24 ± 15.01) when compared with < 2 cm (180.88 ± 17.56 - p = 0.0053) and with 2-4 cm (174.80 ± 15.51 - p = 0.0014) (Table 3).