A recent study used accelerated senescence OXYS rats, which simulate the main features of the sporadic form of AD, to explore the mitochondrial ultrastructure of pyramidal neurons of the CA1 region of the hippocampus and measured the levels of the key proteins involved in mitochondrial dynamics (Mfn1, Mfn2, and Drp1) [40]. The gene discussed is DNM1L; the disease is Alzheimer disease.