TNF and infection: Also, miRNAs that are deregulated during infection, such as miR-30e and miR-302d, interfere with Nos2 mRNA expression and NO production; miR-294 and miR-302d regulate Tnf mRNA levels and miR-294 alters Ccl2/Mcp-1 mRNA, implicating the expression of these miRNAs in controlling infectivity [80].