IL23R and inflammatory bowel disease: Furthermore, mucosal T-cells from patients with IBD express the Th17 cell-associated surface markers CD161 and IL-23 receptor (IL-23R), and the Th17 cell-associated transcription factors retinoic acid receptor-related orphan receptor-γt (RORγt; encoded by RORC), STAT3 and IRF4 [148,164].