RBFOX3 and spinal cord ischemia: Lu et al. have reported that spinal cord ischemia by thoracic aortic occlusion induces histopathological changes in spinal neurons, such as eosinophilic or condensed cytoplasm, and a significant loss of neurons (NeuN-immunoreactive neurons) in the ventral horn of the lumbar spinal cord from 1 day (around 1–3 days) after spinal cord ischemia [27].