For instance, a recent study revealed that linc-GALH (Gankyrin associated lincRNA in hepatocellular carcinoma), which might be a new biomarker for judging HCC metastasis, could promote the degradation of DNMT1 (DNA methyltransferase 1) by enhancing the ubiquitination and expression of Gankyrin (standard nomenclature is PSMD10) by lowering the methylation state in HCC [18]. The gene discussed is DNMT1; the disease is hepatocellular carcinoma.