STAT3 and hepatocellular carcinoma: A recent study revealed that lncRNA TSLNC8 (also known as LINC00589) exerts its tumor suppressive activity through the inactivation of the IL-6/STAT3 signaling pathway via physically interacting with TKT and STAT3, and thus inhibiting STAT3 phosphorylation and transcriptional activity in HCC [36].