For instance, lncRNA HCAL (HCC-associated lncRNA) promotes HCC metastasis by competitively binding to miR-15a, miR-196a, or miR-196b and by subsequently increasing LAPTM4B (lysosomal-associated transmembrane protein 4B) expression (Figure 1D) [37]. The gene discussed is LAPTM4B; the disease is hepatocellular carcinoma.