LncRNA MIR22HG (MIR22 host gene) repressed HCC metastasis by deriving miR-22 and binding with human antigen R (HuR) to increase MIR22HG stability, alter subcellular location of HuR, and decrease the binding abilities of HuR with oncogene mRNAs (Figure 1E) [28]. This evidence concerns the gene ELAVL1 and hepatocellular carcinoma.