We found that the endogenous mRNA levels of H2AFJ and MGMT were causally associated (Figure 3A) and significantly (p = 0.05) correlated with the 50% inhibitory concentration (IC50) of TMZ (Figure 3B) but not the cytotoxic effectiveness of radiation (Figure 3C,D) in the analyzed GBM cell lines. The gene discussed is MGMT; the disease is glioblastoma.