MAPK8 and colorectal carcinoma: Consistent with previous results, increased JNK protein phosphorylation by TAX and NOC was detected in human CRC cells, and application of the JNK inhibitors SP600125 or JNKI protected CRC cells from TAX- and NOC-induced apoptosis and G2/M arrest, accompanied by decreased phosphorylation of Cdc25C and cycB1 protein expressions.