Quercetin reduced the levels of FGF23, PTH, inorganic phosphate and urinary protein-to-creatinine ratios and urinary uric acid, creatinine and blood urea nitrogen, as well as increasing the expression of serum lactate dehydrogenase (LDH), SOD and total antioxidant activity, in an adenine-induced CKD rat model [129]. This evidence concerns the gene PTH and chronic kidney disease.