F8 and hemophilia A: Siegemund et al. demonstrated that TG (ETP) in PRP from patients with severe hemophilia A was not significantly different from patients with severe hemophilia B (FVIII/FIX:C < 2%), although the influence of platelet count on TG parameters appeared to be stronger in hemophilia B. Typically, the effect of platelets on ETP becomes less pronounced with higher FVIII or FIX levels [40].