We discovered that TMP195 resensitizes ABCB1-overexpressing cancer cells to paclitaxel, colchicine, and vincristine (Table 2), as well as resensitizes ABCG2-overexpressing cancer cells to mitoxantrone, SN-38, and topotecan (Table 3) in a concentration-dependent manner. This evidence concerns the gene ABCG2 and cancer.