ABCB1 and ovarian cancer: We discovered that in addition to paclitaxel, TMP195 resensitized KB-V-1 cells and NCI-ADR-RES, an ABCB1-overexpressing MDR variant of OVCAR-8 human ovarian cancer cells, to ABCB1 drug substrates colchicine and vincristine [23,24] as well (Table 2).