Moreover, the observation of no changes in the percentages of CD11b+ F4/80− cells (i.e., Mo of non-embryonic origin) in any of the treatment group (Figure 2C,G) provided further support to the findings in Figure 1, and confirmed that HSC-derived Mo did not contribute to sinusoidal Mφ response in Chagas disease. Here, ITGAM is linked to Chagas disease.