Analysis of pro-inflammatory mRNA purified from kidney from mice infected via NM, TD and IP showed significant increases (p<0.01 to p<0.0001) of innate response chemokine and cytokine mediators (CxCL1/KC, CxCL2/MIP-2, CCL5/RANTES, TNF-α) and Th1 IFN-γ but not from mice infected via OM or from controls (Ctrl). This evidence concerns the gene IFNG and ocular melanoma.