In the Mas Liver (GSE14323), COL4A1 was overexpressed in liver cirrhosis (fold change = 4.233, p = 2.78E-13) and HCC (fold change =3.759, p = 1.40E-12), while COL4A2 was higher expressed in liver cirrhosis (fold change = 2.487, p = 7.88E-14) and HCC (fold change =3.492, p = 1.01E-10) versus normal tissues (Figure 1A and Supplementary Figure 1B). Here, COL4A2 is linked to hepatocellular carcinoma.