COL4A2 was also increased in cirrhosis (fold change =3.412, p = 2.02E-6), liver cell dysplasia (fold change =2.223, p = 1.35E-4), and HCC (fold change =3.154, p = 7.07E-7) compared to normal tissues (Supplementary Figure 1A and 1C). This evidence concerns the gene COL4A2 and hepatocellular carcinoma.