Several PET studies using [18F] FEDAC in rodent models have shown in vivo specific binding with TSPO and high radioactive signals in TSPO‐rich organs.19, 39 In contrast, the uptake of [18F] FEDAC in healthy CNS is reported to be much lower.40 Therefore, PET with [18F] FEDAC has the potential to detect early CNS disorders related to TSPO. The gene discussed is TSPO; the disease is central nervous system disorder.