CXCL12 and endometriosis: Similarly, blocking CXCR7 by CCX771 reduces angiogenesis in vivo interrupting the pro‐angiogenic CXCL12‐CXCR7 autocrine loop exerted by activated endothelial cells.62 Additional studies using CXCR4 and CXCR7 knockout mouse donor tissue would clarify the role of specific cell populations in endometriosis regression following AMD3100 and CCX771 treatment.