We tested the impact ACA has on Apc+/Min mice and found that Apc+/Min males fed either 296 ppm (p = .045) or 935 ppm (p = .0002) diets exhibited enhanced survival compared with control but only mice fed the high ACA‐dose diet showed a modest reduction in tumor number and a modest normalization of hematocrit. Here, APC is linked to neoplasm.