IL1B and asthma: This study explored the expression of the gene signatures 6GS and TH2S previously reported in sputum and epithelial brushings in endobronchial.2, 13 We observed upregulation of two genes of the 6GS, an upregulation of DNASE1L3 in asthma compared with HC, and upregulation of IL1B in neutrophilic asthma compared with non‐neutrophilic asthma.