For example, target genes of BAP1 deubiquitination include mutant ATRX in myeloid neoplasms [25] and Krüppel-like factor 5 (KLF5) in basal-like breast cancers [24], which both become stabilized by BAP1 and consequently accelerate tumor growth [24, 25]. This evidence concerns the gene KLF5 and neoplasm.