To address whether the correlation between MSI1/AGO2 pathway and tumor recurrence could be generalized to other cancer types, we collected samples from patients with pancreatic ductal adenocarcinoma (PDAC) and performed IHC staining of MSI1 on non-recurrent (n = 18) and recurrent (n = 61) PDAC samples (Table S4). This evidence concerns the gene AGO2 and pancreatic ductal adenocarcinoma.