We selected miR-429 as a possible therapeutic molecule, being the only upregulated miRNA among the three, and having a high degree centrality in controlling differentially expressed genes involved in "HIF1 signaling", "Acute Phase Response signaling", "Glioblastoma Multiforme signaling", "P2Y Purigenic Receptor signaling", "CXCR4 signaling " and “Growth hormone signaling”. The gene discussed is HIF1A; the disease is glioblastoma.