For example, if the transcription of a tumor suppressor gene FENDRR, functioning as a competing endogenous RNA to compete binding site with miR-424 towards FOXF1, is inhibited, the miR-424 will depress the translation of FOXF1 by sequence matching to 3’ UTR of its mRNA, resulting in increased lung cancer risk [48]. The gene discussed is FOXF1; the disease is lung carcinoma.