However, in the hippocampus, we found a significant increase in the expression of microglial markers IBA-1 (P < 0.05) and CD 11B (P < 0.05) and astrocyte marker GFAP (P < 0.05) in the meningitis group after 24 h of infection (Fig. 3). The gene discussed is GFAP; the disease is meningitis.