The same group of authors [126] also showed that tumor morphology on CT could differentiate between the two most common subtypes of EGFR mutation, exon 19 deletions, and exon 21 mis-sense mutations; specifically, the ground glass portion of lesions were higher in lesions with exon 21 missense mutations compared with both wild type lesions and tumors with exon 19 deletions. This evidence concerns the gene EGFR and neoplasm.