We previously showed that severe RSV infection in early life was associated with a high incidence of asthma and eczema; however, it was not associated with a Th2 phenotype in the peripheral blood.27 A recent birth cohort study by Turi, et al have demonstrated infants who are at increased risks for recurrent wheeze in the first and second year following acute RSV infection had a unique pattern of nasal immune response characterized by lower non‐IFN antiviral immune‐response mediators including TNF‐α and higher type‐2 and type‐17 cytokines.9 This evidence concerns the gene IFNA1 and Eczematoid dermatitis.