ERBB2 and cancer: This analysis revealed a total of 638 cancer driver genes specific to individual subtypes: luminal A (221 oncogenes and 180 tumor suppressors); luminal B (51 oncogenes and 73 tumor suppressors); basal-like (14 oncogenes and 76 tumor suppressors); HER2-enriched (8 oncogenes and 15 tumor suppressors) (Fig. 2e; Supplementary Data 5).