We did not observe any odontogenic tumours in mice lacking the K5-IKKβ transgene, independently of the p53 or p16/p19 genetic background, or in K5-IKKβ mice bearing wt copies of p53 and Ink4a/Arf (Fig. 2e, f). The gene discussed is CDKN2A; the disease is odontogenic neoplasm.