Using immunohistochemistry technique, we found that VEGF positive cells was anabatic in tumor tissues of nude mouse carrying with the vector expressing LINC00662 transfected HCT29 cells and was declined in tumor tissues of nude mouse carrying with siRNA-LINC00662 transfected CT26 cells, compared to vector or siRNA group (Fig. 4h). The gene discussed is VEGFA; the disease is neoplasm.