FAM13A and cystic fibrosis: Initially, FAM13A was genetically associated with the lung function phenotype [2], with FAM13A genetic variants shown to be associated with lung cancer [3, 4] and several chronic lung diseases including chronic obstructive pulmonary disease (COPD) [5], cystic fibrosis (CF) [6], and idiopathic pulmonary fibrosis (IPF) [7].