Notably, all EMPD cases from our cohort were MSI stable (by NGS and IHC), which is in stark contrast to the study of Kang et al that showed that 8/20 EMPD harbored germline mutations of mismatch repair genes (MMR), five of which were MSI‐H.40 However, both studies have rather limited number of cases studied, and vigilance about MSI status in EMPD is warranted. Here, MRC1 is linked to extramammary Paget disease.