In the case-control study of stroke, the frequencies of all DIAPH1 SNPs in controls were consistent with HWE. Table 2 shows the results of the association analyses after adjusting for age, gender, smoking status, drinking status, TC, TG, LDL-C, HDL-C, T2DM, and hypertension. The gene discussed is DIAPH1; the disease is hypertensive disorder.