To delve deeper into the mechanism of how loss of RBP-J affects retinoid metabolic process genes expression in HFSCs, we performed Assay for Transposase-Accessible Chromatin using sequencing (ATAC-seq) using FACS isolated HFSCs from WT and Krt6-CreER::RBP-J cKO HFs. The gene discussed is RBPJ; the disease is Hand-foot syndrome.