Several lines of evidence suggest that NF‐kB plays a pivotal role in myocardial remodeling by regulating inflammation and cell death; however, additional pathways identified in our analysis, such as the Gαq and prolactin pathways (Tables 2 and 3), are also involved in such remodeling, especially in cardiac hypertrophy 24, 25. The gene discussed is GNAQ; the disease is cardiac hypertrophy.