Next, we examined SRPK2 protein and mRNA expression by Western blotting and qRT-PCR in 24 CRC cases, again finding elevated expression in tumors compared with matched adjacent nontumor tissues (t = 3.631, P = 0.001; t = 3.021, P = 0.006) (Figure 1C,D). The gene discussed is SRPK2; the disease is colorectal carcinoma.